NovImmune masters three different, established and
validated technologies in house:
The UltiMAb system to obtain fully human therapeutic monoclonal
antibodies using transgenic mice (technology licensed from Medarex),
Antibody display selection, that is the selection of fully human
antibodies displayed on bacteriophages (technology pioneered and developed
by CAT)
Humanization, that is the grafting of the small
sequences responsible for the recognition and binding of the antigen from a
non-human species to a fully human mAb backbone